In Vitro Fertilization (IVF) Over 40 Mexico

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In Vitro Fertilization (IVF) Over 40 in Mexico

At IMI – Mexican Institute of Infertility, we believe age does not define your ability to create life. For many women in their 40s, the dream of becoming a mother feels out of reach—but with modern reproductive science, compassionate doctors, and individualized protocols, that dream remains very possible.

Whether you’re 42 and just starting your fertility journey or 47 and ready to try again with donor eggs, our expert team in Guadalajara and Puerto Vallarta will help you take the next step with clarity and confidence.

Travel & Treatment Planning

Most IVF-over-40 patients from abroad complete their treatment within a 2-week stay. IMI’s International Patient Team coordinates your entire journey:

Pre-cycle consultations via video call
Medication shipment and monitoring from home
Airport pickup and hotel arrangements
Daily transport to the clinic
Post-transfer care instructions

Visit IVF in Mexico for travel tips and accommodation guides.

Empowering Motherhood at Every Age

Understanding Fertility After 40

Female fertility naturally declines with age as egg quantity and quality decrease. By age 40, many women have a limited number of healthy eggs remaining, which can lead to:

Fewer viable embryos per cycle
Increased chromosomal abnormalities
Higher risk of miscarriage
Lower implantation rates

However, advances in IVF technology, genetic testing, and laboratory culture have dramatically improved outcomes for patients over 40. At IMI, we combine cutting-edge protocols with personalized care so you can make informed choices and maximize your chances of success.

Why Choose IMI for IVF After 40?

Expert team: Reproductive endocrinologists trained in advanced age fertility protocols.
Personalized care: Every hormone, dose, and embryo decision is tailored to you.
High-tech lab: ICSI, PGT-A, and time-lapse monitoring to maximize embryo potential.
Integrated support: Nutrition, wellness, and mind-body programs.
Proven outcomes: Hundreds of successful pregnancies from patients over 40 worldwide.

How IMI Optimizes IVF for Women Over 40

Comprehensive Pre-Treatment Evaluation

Every patient over 40 begins with a thorough fertility assessment: • Hormonal panel (FSH, LH, AMH, estradiol) • Antral follicle count (AFC) ultrasound • Uterine and endometrial evaluation • Partner sperm analysis and DNA-fragmentation testing This allows our specialists to create a custom protocol based on your true ovarian potential.

PGT-A Genetic Testing

At this age, chromosomal screening is critical. Pre-implantation Genetic Testing for Aneuploidy (PGT-A) identifies healthy embryos before transfer, reducing the risk of miscarriage and improving live-birth rates.

Individualized Ovarian Stimulation

We design stimulation plans using adjusted doses of gonadotropins to encourage optimal egg production without over-stimulation. For some patients, we may use a mild or Mini IVF approach to protect egg quality.

Supportive Hormonal Therapies

We carefully manage thyroid, vitamin D, and progesterone levels to optimize implantation. If needed, our team adds coenzyme Q10, DHEA, and other adjunct treatments to enhance egg mitochondrial function.

Advanced Fertilization Techniques

Our embryologists employ ICSI, PICSI, or PIEZO ICSI to ensure the best possible fertilization even with limited egg numbers. For cases with significant egg quality decline, donor eggs can be used to enhance success rates dramatically.

IMI Mexico combines world-class fertility expertise, advanced reproductive technology, transparent and compassionate care, and proven success in complex cases — all within a modern, internationally trusted clinic in Guadalajara.

Personalized fertility care led by world-class IVF specialists

Cutting-edge reproductive technology that maximizes success rates

Transparent communication, honest guidance, and compassionate support from day one

Proven success with complex and previously unsuccessful fertility cases

State-of-the-art clinic in Guadalajara — Mexico’s leading destination for fertility care

Programs designed for international patients seeking comfort and confidence abroad

Inclusive programs for all, including 40+ and a proud commitment to serving the LGBTQ+ community

Accessible excellence — program costs up to 70% less than U.S. fertility clinics

Multilingual staff ensuring clear communication from consultation to transfer.

Donor Egg IVF for Women Over 40

For patients with diminished ovarian reserve or poor egg quality, egg donation offers a high-success alternative. IMI works with a comprehensive network of healthy, pre-screened donors who undergo extensive medical and genetic testing.

Using donor eggs significantly improves outcomes:

Live birth rates of 70–80 %
Lower risk of chromosomal abnormalities
Greater number of high-quality embryos

Donor-egg IVF still allows you to carry the pregnancy and experience motherhood fully. Our team handles all legal, ethical, and logistical details with complete transparency.

Learn more about our Egg Donation Program in Mexico.

Realistic Expectations and Success Rates

At IMI, we believe in honesty and data-driven guidance. While success with your own eggs declines after age 40, we’ve helped many women conceive through advanced protocols or donor cycles.

Age Range	Average Success Rate (Own Eggs)	With Donor Eggs
40 – 42	35 %	75 %
43 – 45	20 %	70 %
46 +	< 10 %	65 %

These percentages represent average clinical pregnancy rates based on data from our lab and comparable centers.

Emotional and Psychological Support

Trying to conceive over 40 can be emotionally complex. IMI offers on-site and virtual fertility counseling to help you manage expectations, reduce stress, and build emotional resilience. Many patients find that the intimate, calm environment of our clinics in Mexico helps them reconnect with hope and self-trust.

Q1. Is it possible to get pregnant naturally after 40?

Yes, but chances are lower. IVF with personalized stimulation significantly increases the probability of pregnancy.

Q2. Will I need donor eggs?

Not necessarily. Some women conceive using their own eggs with IMI’s advanced protocols. If egg quality is low, donor options are discussed openly and compassionately.

Q3. Does age affect pregnancy health risks?

Older mothers can face higher risks for gestational diabetes or hypertension, but our team monitors you closely and coordinates care with your OB-GYN at home.

Q4. How many embryos are transferred for women over 40?

Typically 1–2 embryos depending on embryo quality and PGT-A results. Our goal is a safe, single healthy pregnancy.

Q5. What is the oldest age for IVF in Mexico?

There is no strict legal limit, but IMI accepts patients’ case-by-case up to age 50 following medical evaluation.

Johannes Times

New York, USA

“I underwent a complex surgery here, and the expertise of the medical team was exceptional. Their follow-up care and support made my recovery faster and easier than I imagined. I’m truly grateful.”

Rachel Jackson

Chikago, USA

“The neurologists here are outstanding. They listened patiently and explained everything in simple terms. I feel confident and cared for.”

Jack Ferguson

Los Angeles, USA

"The doctors were incredibly knowledgeable, and the nurses treated me with kindness and respect every step of the way. I’m so grateful for the outstanding service and compassion I received!"